Stem Cell Derived Exosome Treatments for Thinning Hair

The study of exosomes is an active area of research with many potential applications. Exosomes are naturally occurring extracellular vesicles (EV’s) or “nano-bubbles” that are released by various cells in the body. They contain a variety of nucleic acids, proteins, lipids and metabolites. The EV’s are involved in the communication between cells and affect various aspects of cell biology, immune response, as well as health and tissue repair.


Health Canada has been closely monitoring the use of stem cell derived products for regenerative purposes and has recently approved the use of exosomes in aesthetic medicine. The exosomes’ biocompatibility ensures minimal risk of adverse reactions to the user and they represent a promising avenue in the field of cellular repair and regeneration.


Stem cells are isolated from a variety of donor tissue including the chorion, placenta, and fat and bone marrow. Their source depends on their purpose and the manufacturing company. The stem cells undergo expansion and are then used for the harvesting and production of the exosomes. The potency, quality and reliability of the exosomes are tied to the integrity of the manufacturing process. EV products need to be transported and stored in a temperature-controlled environment to ensure their stability, integrity and optimal performance.


In recent years exosome products have been used as an effective non-invasive treatment option to stimulate hair growth and to promote hair rejuvenation. They are usually applied during and/or after gentle microneedling of the scalp. A numbing cream is applied to anesthetize the scalp in preparation for the treatment. The start of new hair growth can be expected around the fourth month. The number of treatments will vary depending on the concentration of the exosome product that is applied.


This pioneering research is allowing significant strides in the rejuvenation of hair, and promising exciting advancements in the field of regenerative medicine.

De HAAR Hair